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 Primary Hemostasis |
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Platelet Secretion
Activation and adhesion are followed by the secretion
of substances that drive the hemostatic process
by stimulating other platelets to adhere, aggregate,
and secrete.1 When activation
and primary adhesion have been achieved, platelets
commence discharge of granule contents. Granule
contents include ADP, adenosine triphosphate (ATP),
serotonin, calcium, vWF, Factor V, and fibrinogen.
The secreted substances further promote formation
of the platelet plug by means of stimulating other
platelets to adhere, aggregate and secrete.1
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